Lawyer Robert M. Kaplan, graduated from Rutgers University, B.A., 1977 Rutgers University Law School, J.D., 1980, is now employed by Margolis Edelstein at 100 Century Parkway, Suite 200 Mount Laurel, NJ 08054. This shift also aims to motivate other large government and private payors to accelerate the adoption of value-based care through TRICARE's example. OBJECTIVE: The study examined whether comorbid low mental health functioning inflates the cost of treating a chronic disease.METHODS: Data were from the 2015 Medical Expenditure Panel Survey (N=33,893). Symptoms of lack of positive affect decreased more in men compared to women, particularly in those possessing the 5-HTT L allele, but the effect did not differ by intervention arm. View details for PubMedCentralID PMC4145029, View details for DOI 10.1016/j.jamda.2014.05.008, View details for Web of Science ID 000341167700011, View details for PubMedCentralID PMC4145029. Optional sessions were offered during maintenance weeks (25-52). Participants with insomnia had a mean ISI score of 12.1, those with daytime drowsiness had a mean ESS score of 12.5, and those with poor sleep quality had a mean PSQI score of 9.2. Wanigatunga, A. The goal of TRICARE's move toward value-based care is to leverage its size and focus on prevention of disease and injury to maintain the readiness of the U.S. Armed Forces in addition to delivering great outcomes and value to the DoD's nearly 10 million beneficiaries. Robert M. Kaplan, Ph.D. is a Distinguished Professor of the Health Services at UCLA and Distinguished Professor of Medicine at the UCLA David Geffen School of Medicine. Using data from the nationally representative Medical Expenditures Panel Survey (MEPS), we explored the extent to which health care utilization and health risk-taking, together with previously examined mediators, can explain the education-health gradient above and beyond what can be explained by previously examined mediators such as age, race, and poverty status.Health was measured using the Physical Component Score (PCS) from the Medical Outcomes Study 12-Item Short Form (SF-12). Of the 173 total ClinicalTrials.gov records identified across the five projects, between 11 and 43% did not have an associated publication. Losing the ability to walk safely and independently is a major concern for many older adults. View details for DOI 10.2217/cer-2020-0149. Robert D. Kaplan Dr. Duyeon Kim Dr. Daniel Kliman Michael Kofman Christopher D. Kolenda Margarita "Rita" Konaev Steven Kosiak Dr. Andrew F. Krepinevich, Jr. Peter L. Levin Jennifer McArdle Brendan McCord Dr. ED McGrady Jack Midgley J Travis Mosier Dr. Go Myong-Hyun Catherine A. Novelli Dr. John Park Ben Renda Elina Ribakova Diem Salmon View details for DOI 10.1016/j.amepre.2018.09.006, View details for Web of Science ID 000453383700020, View details for Web of Science ID 000498593400292. Participants performed a usual-paced 400-m walk every 6months. Mr. Kaplan holds degrees from Cape Town University and Columbia University. Lower mental health functioning also had a significant impact on cost. Medical tests - whether true or false - generate strong psychological messages. Early diagnosis does not assure application of an intervention that alters the pathway toward demise. However, variability exists in seniors' responsiveness to training. Robert D. Kaplan - Career Reflections Author. Lastly, the IBMT group had stronger brain connectivity between the dorsal anterior cingulate cortex (dACC) and the striatum at resting state, as well as greater volume of gray matter in the striatum. Economic Benefit of "Modern" Nonemergency Medical Transportation That Utilizes Digital Transportation Networks. Moreover, the concept of what constitutes "moderate" exercise or an appropriate volume of work is dictated by the physical capacities of each individual and the level of comfort/stability in actually executing a specific prescription. Behavioral interventions often use measures that are not generally applied in other areas of health outcomes research. A., Ahn, D. K., Gill, T. M., Miller, M., Newman, A. You can email or call Law Offices of Robert M. Kaplan to arrange a meeting with a lawyer in one of their offices at 1535 W Schaumburg Rd. Estimates of the effect of behavioral factors ranged from 16% to 65%.CONCLUSIONS: The results converge to suggest that restricted access to medical care accounts for about 10% of premature death or other undesirable health outcomes. Using hospital discharge data for the period 2007-16, we compared acute myocardial infarction (AMI) hospitalization rates in San Diego County and the rest of the state before and after the demonstration project started. The odds of having MetS or its individual components were similar in obese and nonobese, combined or not with dynapenia (nonsignificant odds ratio [95% confidence interval]).Nonobese dynapenic older adults had fewer metabolic disease risk factors than nonobese and nondynapenic older adults. B., Fielding, R. A., Siordia, C., Moore, S., Folta, S., Spring, B., Manini, T., Pahor, M. Effects of a one-year physical activity program on serum C-terminal Agrin Fragment (CAF) concentrations among mobility-limited older adults. Linking among different measures and consensus on standard HRQoL measurement should now be prioritized. Measures of physical function included usual-paced gait speed and performance on the Short Physical Performance Battery (SPPB). View details for DOI 10.1377/hlthaff.2018.0443, View details for Web of Science ID 000463962900016. A preliminary cost/effectiveness analysis gauged the cost/disability avoided to be $28,206. Epidemiological evidence suggests that physical activity benefits cognition, but results from randomized trials are limited and mixed.To determine whether a 24-month physical activity program results in better cognitive function, lower risk of mild cognitive impairment (MCI) or dementia, or both, compared with a health education program.A randomized clinical trial, the Lifestyle Interventions and Independence for Elders (LIFE) study, enrolled 1635 community-living participants at 8 US centers from February 2010 until December 2011. His Randomized controlled trial research integrates issues from Clinical trial, Intensive care medicine, Pharmacotherapy, Evidence-based practice and Social support. Robert M Kaplan Forensic Psychiatrist, Crime & Medicine Writer, Historian and Speaker at Dr Robert Kaplan Greater Sydney Area 112 followers 97 connections Join to connect Dr Robert. View details for DOI 10.1093/gerona/glw001, View details for Web of Science ID 000376398400015. (Am J Public Health. In this special section, we acknowledge a wide range of variability in terms of behavioral interventions typically delivered in nonclinical versus more traditional clinical settings. The purpose of this study was to examine the relationship between dynapenia and metabolic risk factors in obese and nonobese older adults.A total of 1453 men and women (age 70years) from the Lifestyle Interventions and Independence for Elders (LIFE) Study were categorized as (1) nondynapenic/nonobese (NDYN-NO), (2) dynapenic/nonobese (DYN-NO), (3) nondynapenic/obese (NDYN-O), or (4) dynapenic/obese (DYN-O), based on muscle strength (Foundation for the National Institute of Health criteria) and body mass index. However, further study is needed to definitively determine the utility of CAF as a biomarker of physical function. Fragoso, C. A., Miller, M. E., Fielding, R. A., King, A. C., Kritchevsky, S. B., McDermott, M. M., Myers, V., Newman, A. Wednesday, May 31, 2017. Developed by Harvard Professor, Robert Kaplan and Dr. Dave Norton, the Balanced Scorecard is widely considered as the definitive model for translating strategy into action. These null results were accompanied by suggestive evidence that the physical activity program may reduce the rate of fall related fractures and hospital admissions in men.Trial registration ClinicalsTrials.gov NCT01072500. We had a great time on holiday in Kwazulu-Natal as well. Cost analyses were conducted from the "payer's" perspective, with a 1-year time horizon. Comparison of Rating Scale, Time Tradeoff, and Conjoint Analysis Methods for Assessment of Preferences in Prostate Cancer. INTRODUCTION: Older adults are a rapidly growing segment of the U.S.POPULATION: Mobility problems that lead to further disability can be addressed through physical activity interventions. In order to make better use of scarce resources, cost-effectiveness methodologies have been developed to evaluate how to produce the most health within the constraints of available resources. Sun 5 March, 9:30 - 12:30. The number of older adults living in the United States continues to increase, and recent research has begun to target interventions to older adults who have mobility limitations and are at risk for disability. Behavioral interventions can be offered within a wide range of contexts, including public health, medicine, surgery, physical rehabilitation, nutrition, and other health services. Competing interests: None declared Competing interests: No competing interests 20 February 2004 Robert M Kaplan psychiatrist 2500 View details for DOI 10.1016/j.jamda.2014.05.008 Bott, N. T., Sheckter, C. C., Yang, D., Peters, S., Brady, B., Plowman, S., Borson, S., Leff, B., Kaplan, R. M., Platchek, T., Milstein, A. Bentley Kaplan Expand search. Fremont, A., Kim, A. Y., Bailey, K., Hanley, H. R., Thorne, C., Dudl, R. J., Kaplan, R. M., Shortell, S. M., DeMaria, A. N. Educational Attainment and Health Outcomes: Data From the Medical Expenditures Panel Survey, Dynapenia and Metabolic Health in Obese and Nonobese Adults Aged 70 Years and Older: The LIFE Study. We investigated whether information in ClinicalTrials.gov would impact the conclusions of five ongoing systematic reviews.We considered five reviews that included 495 studies total. In addition, we review methods used for economic analysis and calculation of the quality-adjusted life year (QALY). Robert M. Kaplan combines subjects such as Diabetes mellitus, Psychiatry, Respondent and Emergency medicine with his study of Quality of life. A., Glynn, N. W., King, A. C., Anton, S. D., Walkup, M., Lu, C., Reid, K., Spring, B., Pahor, M. METHODS FOR QUANTIFYING EFFICACY-EFFECTIVENESS GAP OF RANDOMIZED CONTROLLED TRIALS: EXAMPLES IN ARDS. Our results indicate that mindfulness meditation and physical exercise function in part by different mechanisms, with PE increasing physical fitness and IBMT inducing plasticity in the central nervous systems. He is also director of the UCLA/RAND health services training program and PI of the UCLA/RAND CDC Prevention Research Center. Robert M. Kaplan, Ph.D. is Fred W. and Pamela K. Wasserman Distinguished Professor of the Department of Health Services at UCLA and Distinguished Professor of Medicine at the UCLA David Geffen School of Medicine. Better compliance with mandated reporting and improved reporting standards would facilitate a more comprehensive representation of depression treatment research. Partitioning the MAT-sf into four groups revealed that persons with scores <40, 40-49, 50-59, and 60+ had failure rates across 42 months of follow-up of 66%, 52%, 35%, and 22%, respectively.The MAT-sf is a quick and efficient way of identifying older adults at risk for MMD. Robert D. Kaplan is a senior fellow at the Center for a New American Security and a . Robert M Kaplan Boca Raton, FL (Century Village West) AGE 70s AGE 70s Robert M Kaplan Boca Raton, FL (Century Village West) Aliases Bob L Kaplan Phone NumberAddressBackground Report Aliases Bob L Kaplan Addresses Preston a Boca Raton, FL Eagle Creek Ct Boca Raton, FL James St Aledo, TX Relatives 2018 o 8:00 UTC na Court 2, Stellenbosch, South Africa. Health services researchStudies on the cost and quality of health careHealth outcome measurementSocial determinants of health. Robert Kaplan. Health care has modest effects on the extension of US life expectancy, while behavioral and social determinants may have larger effects. Consistent with prior research, the AS incidence rate was greater in the White population than the Black population (aOR = 1.39, 95% CI 1.01 - 1.66, p = 0.04).CONCLUSION: In this study population, the incidence of AS was similar for the sexes. Robert Kaplan brings together extensive data to make the case that health care priorities in the United States are sorely misplaced. View details for DOI 10.1080/21642850.2021.1979407, View details for PubMedCentralID PMC8462930. Total score was calculated by averaging across questions; baseline fatigue was based on the median split: 2 or higher=more fatigue (N=856) and lower than 2=less fatigue (N=735). When expanded it provides a list of search options that will switch the search inputs to match the current selection. Free delivery worldwide on over 20 million titles. To control for confounding of group participation with survival (because individual sessions preceded group), we used risk set sampling to match minimal survival time of those receiving or not receiving group training.Analyses correcting for differential survival among comparison groups showed that group plus individual therapy was associated with a 33% reduction (hazard ratio=0.67; 95% confidence interval, 0.49-0.92, P=.01) in medical outcome compared to usual care. Report. The results are preliminary and a longer study is required to fully assess the costs and health benefits of these interventions. View details for DOI 10.14283/jfa.2016.76, View details for Web of Science ID 000449826700002, View details for PubMedCentralID PMC4905714. To date, physical exercise is the only intervention consistently demonstrated to attenuate age-related declines in physical function. Groessl, E. J., Kaplan, R. M., Rejeski, W., Katula, J. To examine determinants of racial/ethnic differences in diabetes incidence among postmenopausal women participating in the Women's Health Initiative.Data on race/ethnicity, baseline diabetes prevalence, and incident diabetes were obtained from 158,833 women recruited from 1993-1998 and followed through August 2009. Genealogy for Robert Roman Kaplan (1908 - 1978) family tree on Geni, with over 240 million profiles of ancestors and living relatives. View Details. Associations between these exposures and measured BMI and grip strength were evaluated using linear regression.Greater time spent in light intensity activity and lower sedentary times were both associated with lower BMI. The Lifestyle Interventions and Independence for Elders study recently demonstrated that a physical activity (PA) intervention can delay the onset of major mobility disability. Implementing sobering centers as a treatment alternative for individuals with uncomplicated acute alcohol intoxication could yield substantial cost savings for the U.S. health care system. Serious adverse events were reported by 404 participants (49.4%) in the physical activity group and 373 participants (45.7%) in the health education group (risk ratio, 1.08 [95% CI, 0.98-1.20]).A structured, moderate-intensity physical activity program compared with a health education program reduced major mobility disability over 2.6 years among older adults at risk for disability. Student Workbook for Kaplan/Saccuzzos Psychological Testing: Principles, Applications, and Issues, 7th by Robert M. Kaplan , Dennis P. Saccuzzo ISBN 9780495597742 (978--495-59774-2) These results are consistent with the hypothesis that replacing sedentary activities with light intensity activities could lead to lower BMI levels and obesity prevalence among the population of older adults. View details for DOI 10.1177/0272989X19873667, View details for DOI 10.1007/s11606-019-04998-5, View details for Web of Science ID 000483539200011. The DHB emphasizes that TRICARE's size and focus on providing quality care at lower cost will incentivize providers to participate in the shift toward value-based care despite the potential challenges in transitioning to this system. B., Lifestyle Interventions and Independence for Elders Study Group, Pahor, M., Guralnik, J. M., Anton, S. D., Buford, T. W., Leeuwenburgh, C., Nayfield, S. G., Manini, T. M., Caudle, C., Crump, L., Holmes, L., Lee, J., Lu, C., Miller, M. E., Espeland, M. A., Ambrosius, W. T., Applegate, W., Beavers, D. P., Byington, R. P., Cook, D., Furberg, C. D., Harvin, L. N., Henkin, L., Hepler, J., Hsu, F., Joyce, K., Lovato, L., Pierce, J., Roberson, W., Robertson, J., Rushing, J., Rushing, S., Stowe, C. L., Walkup, M. P., Hire, D., Rejeski, W. J., Katula, J. Kaplan is a past President of five academic societies. Robert D. Kaplan, The Return of Marco Polo's World: War, Strategy, and American Interests in the Twenty-first Century 2 likes Like "Today, despite the jet and information age, 90 percent of global commerce and two thirds of all petroleum supplies travel by sea." Robert D. Kaplan, Monsoon: The Indian Ocean and the Future of American Power These differing services compete for the same resources and it is difficult to compare their value. 104 people named Robert Kaplan found in Boston-Worcester-Lawrence, Springfield and 4 other cities. Each team then evaluated the impact of the evidence found in ClinicalTrials.gov on the conclusions in the review.Across the five reviews, the number of studies that had both a registry record and a publication varied widely, from none in one review to 43% of all studies identified in another. Outcomes were assessed every six months for up to 42 months by staff masked to intervention assignment. Robert Kaplan; Found 609 results for. Results of prior research have been mixed, including findings of a 3:1 incidence ratio for males vs. females, but increasing AS rates among females.METHODS: We estimated the incidence of AS in a retrospective cohort study of diverse, working-age US military service members during March 2014 - June 2017 (N = 728,556) who underwent clinical practice guideline-directed screening for chronic back pain. Contributions of Health Care to Longevity: A Review of 4 Estimation Methods. A., Bailey, C., Charpentier, P., Hawthorne-Jones, G., Mignosa, B., Lewis, L., Williamson, J., Hendrie, H. C., Rapp, S. R., Verghese, J., Woolard, N., Espeland, M., Jennings, J., Wilson, V. K., Pepine, C. J., Ariet, M., Handberg, E., Deluca, D., Hill, J., Szady, A., Chupp, G. L., Flynn, G. M., Hankinson, J. L., Fragoso, C., Groessl, E. J., Kaplan, R. M., LIFE Study Grp. Looking for books by Robert M. Kaplan? Robert M. Kaplan, Dennis P. Saccuzzo. Zero Robert M Kaplan, but end up in harmful downloads. View details for DOI 10.1111/jgs.12738 We performed a budget impact analysis from the perspective of the U.S. health care system based on published and gray literature reports. About the. Clinicians should consider targeted recommendation of physical activity and moderate-intensity exercise for older adults as a treatment to slow decline in eGFRCysC.Trial Registration: ClinicalTrials.gov Identifier: NCT01072500. Robert M. Kaplan, Michael L. Spittel, and Tia L. Zeno Volume 1, Issue 1 https://doi.org/10.1177/2372732214549754 Abstract Tweet Key Points Introduction U.S. Life Expectancy in International Perspective Explanations of the Relationship Between Education and Life Expectancy Relationship Between Education and Changes in Life Expectancy Conclusions The authors wish to acknowledge the support and work done on this project by Christopher Davies Junior. Glassman, J. R., Hopkins, D. S., Bundorf, M. K., Kaplan, R. M., Ragavan, M. V., Glaseroff, A. n., Milstein, A. n. Recommendations for cancer screening would be different if we measured endpoints that are valid, reliable, specific, and important to patients. Porzsolt, F., Wiedemann, F., Phlippen, M., Weiss, C., Weiss, M., Schmaling, K., Kaplan, R. M. Efficacy and effectiveness studies of depression are not well-differentiated in the literature: a systematic review. Lee, C., Scheuter, C., Rochlin, D., Platchek, T., Kaplan, R. M. Effects of Mental Health on the Costs of Care for Chronic Illnesses. Jacobsen, P. B., Prasad, R., Villani, J., Lee, C., Rochlin, D., Scheuter, C., Kaplan, R. M., Freedland, K. E., Manber, R., Kanaan, J., Wilson, D. K. Economic analysis in behavioral health: Toward application of standardized methodologies. We examined characteristics of the transparent reporting of depression treatment studies registered in ClinicalTrials.gov.DESIGN: Cross sectional.SETTING AND PARTICIPANTS: US-based studies identified in a search of ClinicalTrials.gov with depression as the condition, enrolling ages 18 and older, and completed between 1 January 2008 and 1 May 2019.INTERVENTIONS: All interventions were included.MAIN OUTCOMES AND MEASURES: The main outcome was whether any results were reported prior to 1 May 2020. Run Background Search Optout of Search Copy Link. View details for DOI 10.1093/gerona/glr123, View details for Web of Science ID 000296102100011. This pattern of results persisted even after stratifying on the number of self-reported chronic conditions.Our findings provide no evidence that access to and use of health care explains the education-health gradient. View details for DOI 10.1152/physiolgenomics.00169.2013, View details for Web of Science ID 000332245700001, View details for PubMedCentralID PMC3949106. The physical activity and exercise intervention resulted in statistically significantly lower decline in eGFRCysC over 2 years compared with the health education arm (mean difference, 0.96 mL/min/1.73 m2; 95% CI, 0.02-1.91 mL/min/1.73 m2) and lower odds of rapid eGFRCysC decline (odds ratio, 0.79; 95% CI, 0.65-0.97).Conclusions and Relevance: Results of this ancillary analysis of a randomized clinical trial showed that when compared with health education, a physical activity and exercise intervention slowed the rate of decline in eGFRCysC among community-dwelling sedentary older adults. View details for DOI 10.1001/jamainternmed.2022.1449, View details for Web of Science ID 000788118600200. Porzsolt, F. n., Matosevic, R. n., Kaplan, R. M. Long-Term Physical Exercise and Mindfulness Practice in an Aging Population. Rather than reading a good book with a cup of coffee in the afternoon, instead they cope with some infectious bugs inside their desktop computer. We here illustrate a quantification of the difference between objective and subjective risks.The objective risks (or chances) can be obtained from traditional 22 tables by calculating the positive (+LR) and negative (-LR) likelihood ratios. However, more research is necessary to conclusively rule out medical care as a mediator between education and health. Costs for this PA program for older adults are comparable to those of other PA interventions. View details for Web of Science ID 000311424100024, View details for PubMedCentralID PMC3476929. A Phase 3 randomized controlled trial is needed to fill this evidence gap.The Lifestyle Interventions and Independence for Elders (LIFE) Study is a Phase 3 multicenter randomized controlled trial designed to compare a supervised moderate-intensity physical activity program with a successful aging health education program in 1,600 sedentary older persons followed for an average of 2.7 years.LIFE's primary outcome is major mobility disability, defined as the inability to walk 400 m. Secondary outcomes include cognitive function, serious fall injuries, persistent mobility disability, the combined outcome of major mobility disability or death, disability in activities of daily living, and cost-effectiveness.Results of this study are expected to have important public health implications for the large and growing population of older sedentary men and women. These mixed results might reflect heterogeneity in response to physical activity, with some subgroups of individuals responding positively, but not others.1) To examine the impact of genetic variation and sex on changes in depressive symptoms in older adults after a physical activity (PA) intervention, and 2) to determine if PA differentially improves particular symptom dimensions of depression.Randomized controlled trial.Four field centers (Cooper Institute, Stanford University, University of Pittsburgh, and Wake Forest University).396 community-dwelling adults aged 70-89 years who participated in the Lifestyle Interventions and Independence for Elders Pilot Study (LIFE-P).12-month PA intervention compared to an education control.Polymorphisms in the serotonin transporter (5-HTT), brain-derived neurotrophic factor (BDNF), and apolipoprotein E (APOE) genes; 12-month change in the Center for Epidemiologic Studies Depression Scale total score, as well as scores on the depressed affect, somatic symptoms, and lack of positive affect subscales.Men randomized to the PA arm showed the greatest decreases in somatic symptoms, with a preferential benefit in male carriers of the BDNF Met allele. Greater time spent in higher but not lower intensities of light activity (assessed objectively) was associated with greater grip strength in men but not women, while neither objectively assessed nor self-reported sedentary time was associated with grip strength.In this cross-sectional study, greater time spent in light intensity activity and lower sedentary times were associated with lower BMI. Interview: Robert Kaplan, . B., Pahor, M., Gill, T. M. Respiratory Impairment and Dyspnea and Their Associations with Physical Inactivity and Mobility in Sedentary Community-Dwelling Older Persons. Accelerometry data collected during PA training revealed that the average intensity - 1,555 counts/minute for men and 1,237 counts/minute for women - was well below the cutoff point used to classify exercise as being of moderate intensity or higher for adults. Those with less education were also more likely to be uninsured throughout the year. At baseline, the 2 groups were well balanced by age, comorbidity, and baseline eGFRCysC. The SF-12 physical component summary score was a covariate. Participants were randomized to a structured, moderate intensity physical activity program (n=818) conducted in a center (twice a week) and at home (3-4 times a week) that included aerobic, strength, flexibility, and balance training activities, or to a health education program (n=817) consisting of workshops on topics relevant to older people and upper extremity stretching exercises.Serious fall injuries, defined as a fall that resulted in a clinical, non-vertebral fracture or that led to a hospital admission for another serious injury, was a prespecified secondary outcome in the LIFE Study. This paper describes the methods employed in the delivery of the LIFE Study PA intervention, providing insight into how we promoted adherence and monitored the fidelity of treatment. Dismiss. These assessments were used to compare a physical activity intervention with a health education control. Developed under the prevailing zeitgeist of the biomedical model, behavioral and social science has often been underfunded at NIH. Robert A Kaplan, age 70. Our objective is to examine the resources required to deliver the PA intervention and calculate the incremental cost-effectiveness compared with a health education intervention.The Lifestyle Interventions and Independence for Elders study enrolled 1,635 older adults at risk for mobility disability. It could be used to clinically identify older adults that are in need of intervention for MMD and provides a simple means for monitoring the status of patients' mobility, an important dimension of functional health. Bann, D., Hire, D., Manini, T., Cooper, R., Botoseneanu, A., McDermott, M. M., Pahor, M., Glynn, N. W., Fielding, R., King, A. C., Church, T., Ambrosius, W. T., Gill, T. Association of objectively measured physical activity with cardiovascular risk in mobility-limited older adults. He has served as Chief Science Officer at the US Agency for Health Care Research and Quality (AHRQ) and Associate Director of the National Institutes of Health, where he led the behavioral and social sciences programs. Costs were estimated from medical records and self-reported health care use. Bob has taken hundreds of jury trials to verdict, defending clients in premises liability, professional malpractice, products liability, assault, and motor vehicle liability cases. View details for DOI 10.1371/journal.pone.0116058. To determine the effect of a one-year PA intervention on changes in CAF concentrations and to evaluate baseline and longitudinal associations between CAF concentrations and indices of physical function.Ancillary study to the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P), a multi-site randomized clinical trial designed to evaluate the effects of chronic exercise on the physical function of older adults at risk for mobility disability.Four academic research centers within the U.S.Three hundred thirty three older adults aged 70 to 89 with mild to moderate impairments in physical function.A 12-month intervention of either structured physical activity (PA) or health education promoting successful aging (SA).Serum CAF concentrations and objectives measures of physical function - i.e.